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2,111 results

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Page 1
Showing results for pseudomonas macrophage
Search for Pseudomonas mycophage instead (1 results)
TREM2/beta-catenin attenuates NLRP3 inflammasome-mediated macrophage pyroptosis to promote bacterial clearance of pyogenic bacteria.
Wang Y, Cao C, Zhu Y, Fan H, Liu Q, Liu Y, Chen K, Wu Y, Liang S, Li M, Li L, Liu X, Zhang Y, Wu C, Lu G, Wu M. Wang Y, et al. Cell Death Dis. 2022 Sep 6;13(9):771. doi: 10.1038/s41419-022-05193-x. Cell Death Dis. 2022. PMID: 36068223 Free PMC article.
TREM2 deficiency also decreased bacterial killing ratio of macrophage, while Caspase-1 or GSDMD inhibition promoted macrophage-mediated clearance to these bacteria. ...Collectively, TREM2/beta-catenin inhibits NLRP3 inflammasome to regulate macrophage pyropto …
TREM2 deficiency also decreased bacterial killing ratio of macrophage, while Caspase-1 or GSDMD inhibition promoted macrophage …
Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity.
Solis AG, Bielecki P, Steach HR, Sharma L, Harman CCD, Yun S, de Zoete MR, Warnock JN, To SDF, York AG, Mack M, Schwartz MA, Dela Cruz CS, Palm NW, Jackson R, Flavell RA. Solis AG, et al. Nature. 2019 Sep;573(7772):69-74. doi: 10.1038/s41586-019-1485-8. Epub 2019 Aug 21. Nature. 2019. PMID: 31435009 Free PMC article.
Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis.
Neupane AS, Willson M, Chojnacki AK, Vargas E Silva Castanheira F, Morehouse C, Carestia A, Keller AE, Peiseler M, DiGiandomenico A, Kelly MM, Amrein M, Jenne C, Thanabalasuriar A, Kubes P. Neupane AS, et al. Cell. 2020 Oct 1;183(1):110-125.e11. doi: 10.1016/j.cell.2020.08.020. Epub 2020 Sep 3. Cell. 2020. PMID: 32888431 Free article.
During respiration, humans breathe in more than 10,000 liters of non-sterile air daily, allowing some pathogens access to alveoli. Interestingly, alveoli outnumber alveolar macrophages (AMs), which favors alveoli devoid of AMs. If AMs, like most tissue macrophages, …
During respiration, humans breathe in more than 10,000 liters of non-sterile air daily, allowing some pathogens access to alveoli. Interesti …
Pseudomonas-dominant microbiome elicits sustained IL-1beta upregulation in alveolar macrophages from lung transplant recipients.
Britton N, Villabona-Rueda A, Whiteside SA, Mathew J, Kelley M, Agbor-Enoh S, McDyer JF, Christie JD, Collman RG, Cox AL, Shah P, D'Alessio F. Britton N, et al. J Heart Lung Transplant. 2023 Sep;42(9):1166-1174. doi: 10.1016/j.healun.2023.04.005. Epub 2023 Apr 21. J Heart Lung Transplant. 2023. PMID: 37088343
We examined human alveolar macrophage (AMphi) responses to PsA and Pseudomonas dominant microbiome in healthy LTR. METHODS: We stimulated THP-1 derived macrophages (THP-1Mphi) and human AMphi from LTR with different bacteria and LTR BAL derived microbiome cha …
We examined human alveolar macrophage (AMphi) responses to PsA and Pseudomonas dominant microbiome in healthy LTR. METHODS: We …
Lipopolysaccharide from biofilm-forming Pseudomonas aeruginosa PAO1 induces macrophage hyperinflammatory responses.
Wang S, Xiang D, Tian F, Ni M. Wang S, et al. J Med Microbiol. 2021 Apr;70(4):001352. doi: 10.1099/jmm.0.001352. J Med Microbiol. 2021. PMID: 33909550 Free PMC article.
There have been several studies on LPS induced polarization of human and mouse macrophages with different results. And it was reported that the lipid A structure of the LPS derived from biofilm-forming Pseudomonas aeruginosa strain PAO1 was modified.Aim. ...The expr …
There have been several studies on LPS induced polarization of human and mouse macrophages with different results. And it was reporte …
Pseudomonas aeruginosa OprF plays a role in resistance to macrophage clearance during acute infection.
Moussouni M, Berry L, Sipka T, Nguyen-Chi M, Blanc-Potard AB. Moussouni M, et al. Sci Rep. 2021 Jan 11;11(1):359. doi: 10.1038/s41598-020-79678-0. Sci Rep. 2021. PMID: 33432030 Free PMC article.
While considered an extracellular pathogen, Pseudomonas aeruginosa has been reported to be engulfed by macrophages in cellular and animal models. ...We established that P. aeruginosa oprF mutant is attenuated in zebrafish embryos in a macrophage-dependent man …
While considered an extracellular pathogen, Pseudomonas aeruginosa has been reported to be engulfed by macrophages in cellular …
Activating transcription factor 3 involved in Pseudomonas aeruginosa PAO1-induced macrophage senescence.
Zhao Q, Luo YF, Tian M, Xiao YL, Cai HR, Li H. Zhao Q, et al. Mol Immunol. 2021 May;133:122-127. doi: 10.1016/j.molimm.2021.02.016. Epub 2021 Feb 25. Mol Immunol. 2021. PMID: 33640762
Knockdown of ATF3 in macrophage resulted in increased percentage of senescent macrophage under PAO1 infection, while overexpressing ATF3 partly blocked PAO1-induced macrophage senescence. In accordance with the senescent phenotype, elevated reactive oxygen sp …
Knockdown of ATF3 in macrophage resulted in increased percentage of senescent macrophage under PAO1 infection, while overexpre …
Airway immunometabolites fuel Pseudomonas aeruginosa infection.
Riquelme SA, Prince A. Riquelme SA, et al. Respir Res. 2020 Dec 10;21(1):326. doi: 10.1186/s12931-020-01591-x. Respir Res. 2020. PMID: 33302964 Free PMC article. Review.
Pulmonary infections are associated with a brisk inflammatory reaction to bacterial surface components. Lipopolysaccharides (LPS) trigger macrophage activation and release of mitochondrial metabolites that control the intensity of the immune response. ...In this review we …
Pulmonary infections are associated with a brisk inflammatory reaction to bacterial surface components. Lipopolysaccharides (LPS) trigger …
Modulation of macrophage function for defence of the lung against Pseudomonas aeruginosa.
Speert DP, Wong SY, Macdonald M, Sargeant R. Speert DP, et al. Behring Inst Mitt. 1997 Feb;(98):274-82. Behring Inst Mitt. 1997. PMID: 9382751 Review.
We have recently demonstrated that pulmonary alveolar macrophages (as opposed to all other macrophage phenotypes studied) lack the capacity to transport glucose and to phagocytose unopsonized P. aeruginosa; however, after the cells have been cultured in vitro for 48 …
We have recently demonstrated that pulmonary alveolar macrophages (as opposed to all other macrophage phenotypes studied) lack …
Pseudomonas aeruginosa promotes autophagy to suppress macrophage-mediated bacterial eradication.
Wu Y, Li D, Wang Y, Chen K, Yang K, Huang X, Zhang Y, Wu M. Wu Y, et al. Int Immunopharmacol. 2016 Sep;38:214-22. doi: 10.1016/j.intimp.2016.04.044. Epub 2016 Jun 11. Int Immunopharmacol. 2016. PMID: 27295610
OBJECTIVES: To explore the role of autophagy on macrophage-mediated phagocytosis and intracellular killing of Pseudomonas aeruginosa (PA), a common extracellular bacterium which often causes various opportunistic infections. METHODS: Macrophages were infected …
OBJECTIVES: To explore the role of autophagy on macrophage-mediated phagocytosis and intracellular killing of Pseudomonas aeru …
2,111 results